Production of triacylglycerols rich in palmitic acid at sn-2 position by lipase-catalyzed acidolysis

Production of triacylglycerols rich in palmitic acid at position 2 as intermediates for the synthesis of human milk fat substitutes by enzymatic acidolysis

Palmitic acid in the sn-2 position of triacylglycerols acutely influences postprandial lipid metabolism.

BACKGROUND The triacylglycerol structure of saturated fats may influence postprandial lipemia. OBJECTIVE We tested the hypothesis that high-fat meals rich in palmitic acid (16:0) in the sn-2 position decrease lipemia. DESIGN Postprandial changes in plasma lipids, apolipoprotein B48, and cytokines were compared in healthy men (n = 25) and women (n = 25) by using a randomized crossover design...

Dietary Triacylglycerols with Palmitic Acid in the sn-2 Position Modulate Levels of N-Acylethanolamides in Rat Tissues

BACKGROUND Several evidences suggest that the position of palmitic acid (PA) in dietary triacylglycerol (TAG) influences different biological functions. We aimed at evaluating whether dietary fat with highly enriched (87%) PA in sn-2 position (Hsn-2 PA), by increasing PA incorporation into tissue phospholipids (PL), modifies fatty acid profile and biosynthesis of fatty acid-derived bioactive li...

Expression of Castor LPAT2 Enhances Ricinoleic Acid Content at the sn-2 Position of Triacylglycerols in Lesquerella Seed

Lesquerella is a potential industrial oilseed crop that makes hydroxy fatty acid (HFA). Unlike castor its seeds are not poisonous but accumulate lesquerolic acid mostly at the sn-1 and sn-3 positions of triacylglycerol (TAG), whereas castor contains ricinoleic acid (18:1OH) at all three positions. To investigate whether lesquerella can be engineered to accumulate HFAs in the sn-2 position, mult...

structured lipids produced through lipase-catalyzed acidolysis of canola oil

enzymatic acidolysis of canola oil through caprylic acid was investigated to produce certain medium chain ttriacyliglycerol (tag) structured lipids (sls). lipozyme tl im, an sn-1,3 specific thermomyces lanuginosa lipase, and novozym 435, a non-specific candida antarctica lipase, were utilized as the biocatalysts in a batch reactor. reaction conditions were designed according to taguchi’s approa...